DCANP1 Gene Summary [Human]
This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | DCANP1 |
| Official Name | dendritic cell associated nuclear protein [Source:HGNC Symbol;Acc:HGNC:24459] |
| Ensembl ID | ENSG00000251380 |
| Bio databases IDs | |
| Aliases | dendritic cell associated nuclear protein, dendritic cell nuclear protein 1 |
| Synonyms | C5orf20, DCNP1, dendritic cell associated nuclear protein 1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DCANP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DCANP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- genitalia morphogenesis
- genitalia development
- inner ear development
- cochlea development
- trigeminal nerve development
- cochlea morphogenesis
- thorax and anterior abdomen determination
- regulation of muscle organ development
- craniofacial suture morphogenesis
- vestibulocochlear nerve formation
- inner ear morphogenesis
- auditory behavior
- mastication
- peristalsis
- neuromuscular process controlling balance
Cellular Component
Where in the cell the gene product is active
- nuclear body
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding