TRAPPC2B Gene Summary [Human]
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endoplasmic reticulum and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TRAPPC2B |
| Official Name | trafficking protein particle complex 2B [Source:HGNC Symbol;Acc:HGNC:10710] |
| Ensembl ID | ENSG00000256060 |
| Bio databases IDs | |
| Aliases | trafficking protein particle complex 2B, trafficking protein particle complex subunit 2B |
| Synonyms | MIP-2A, SEDLP, SEDLP1, trafficking protein particle complex subunit 2B, TRAPPC2P1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRAPPC2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription factor binding
- Sedlin, N-terminal conserved region
- protein binding
- Longin-like domains
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- intracellular membrane-bounded organelle
- Nucleus
- Endoplasmic Reticulum
- nucleoplasm
- outer nuclear membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRAPPC2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle coating
- ER to Golgi vesicle-mediated transport
- positive regulation of gene expression
- COPII vesicle coating
Cellular Component
Where in the cell the gene product is active
- TRAPP complex
- nucleus
- perinuclear region of cytoplasm
- cytoplasm
- intracellular membrane-bounded organelle
- endoplasmic reticulum
- nuclear outer membrane
- endoplasmic reticulum-Golgi intermediate compartment
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- transcription corepressor binding
- protein binding