MAP1LC3B2 Gene Summary [Human]
Predicted to enable microtubule binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in autophagy of mitochondrion; cellular response to nitrogen starvation; and macroautophagy. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | MAP1LC3B2 |
| Official Name | microtubule associated protein 1 light chain 3 beta 2 [Source:HGNC Symbol;Acc:HGNC:34390] |
| Ensembl ID | ENSG00000258102 |
| Bio databases IDs | |
| Aliases | microtubule associated protein 1 light chain 3 beta 2 |
| Synonyms | ATG8G, microtubule associated protein 1 light chain 3 beta 2, microtubule associated protein 1 light chain 3 β 2 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MAP1LC3B2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubl1_cv_Nsp3_N-like
Pathways
Biological processes and signaling networks where the MAP1LC3B2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MAP1LC3B2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagic vacuole assembly
- mitochondrion degradation
- cellular response to nitrogen starvation
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- endomembrane system
- cytoplasmic vesicle
- autophagic vacuole membrane
- microtubule
Molecular Function
What the gene product does at the molecular level
- phosphatidylethanolamine binding
- ubiquitin protein ligase binding
- microtubule binding