Rtca Gene Summary [Mouse]
Predicted to enable RNA-3'-phosphate cyclase activity. Involved in negative regulation of optical nerve axon regeneration. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in dorsal root ganglion; retina; and retina ganglion cell layer. Orthologous to human RTCA (RNA 3'-terminal phosphate cyclase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rtca |
| Official Name | RNA 3'-terminal phosphate cyclase [Source:MGI Symbol;Acc:MGI:1913618] |
| Ensembl ID | ENSMUSG00000000339 |
| Bio databases IDs | |
| Aliases | RNA 3'-terminal phosphate cyclase |
| Synonyms | 2310009A18Rik, RNA 3'-terminal phosphate cyclase, RPC, RTC1, RTCD1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rtca often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 18S rRNA biogenesis protein RCL1
- RNA 3'-terminal phosphate cyclase
- RNA-3'-phosphate cyclase
- RNA 3'-phosphate cyclase
- enzyme
- protein binding
- RNA 3'-terminal phosphate cyclase (RTC), insert domain
- EPT_RTPC-like
- RNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rtca gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- RNA-3'-phosphate cyclase activity
- RNA binding