RTCA Gene Summary [Human]
This gene encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Details
| Type | Processed Transcript |
| Official Symbol | RTCA |
| Official Name | RNA 3'-terminal phosphate cyclase [Source:HGNC Symbol;Acc:HGNC:17981] |
| Ensembl ID | ENSG00000137996 |
| Bio databases IDs | |
| Aliases | RNA 3'-terminal phosphate cyclase |
| Synonyms | 2310009A18Rik, RNA 3'-terminal phosphate cyclase, RPC, RTC1, RTCD1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RTCA often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 18S rRNA biogenesis protein RCL1
- RNA 3'-terminal phosphate cyclase
- RNA-3'-phosphate cyclase
- RNA 3'-phosphate cyclase
- enzyme
- protein binding
- RNA 3'-terminal phosphate cyclase (RTC), insert domain
- EPT_RTPC-like
- RNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RTCA gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- RNA-3'-phosphate cyclase activity
- RNA binding