N4bp3 Gene Summary [Mouse]
Predicted to be involved in nervous system development. Predicted to act upstream of with a positive effect on innate immune response. Located in cytoplasmic vesicle. Is expressed in several structures, including central nervous system; eye; gut; lung; and reproductive system. Orthologous to human N4BP3 (NEDD4 binding protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | N4bp3 |
| Official Name | NEDD4 binding protein 3 [Source:MGI Symbol;Acc:MGI:2442218] |
| Ensembl ID | ENSMUSG00000001053 |
| Bio databases IDs | |
| Aliases | NEDD4 binding protein 3 |
| Synonyms | C330016O10Rik, LOC103689949, LZTS4, NEDD4 binding protein 3, RGD1308356 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse N4bp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Fez1
- protein binding
- proline rich domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- vesicles
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse N4bp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- nervous system development
Cellular Component
Where in the cell the gene product is active
- dendrite
- cytoplasmic vesicle
- axon
Molecular Function
What the gene product does at the molecular level
- protein binding