Taco1 Gene Summary [Mouse]
Enables mRNA binding activity; mitochondrial ribosome binding activity; and rRNA binding activity. Acts upstream of or within several processes, including mitochondrial cytochrome c oxidase assembly; motor learning; and regulation of cytochrome-c oxidase activity. Located in mitochondrion. Is expressed in several structures, including alimentary system; nervous system; nose; orbito-sphenoid; and pharyngo-tympanic tube. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 8. Orthologous to human TACO1 (translational activator of cytochrome c oxidase I). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Taco1 |
| Official Name | translational activator of mitochondrially encoded cytochrome c oxidase I [Source:MGI Symbol;Acc:MGI:1917457] |
| Ensembl ID | ENSMUSG00000001983 |
| Bio databases IDs | |
| Aliases | translational activator of mitochondrially encoded cytochrome c oxidase I |
| Synonyms | 2310066I18Rik, CCDC44, LOC51204, MC4DN8, RGD1306784, translational activator of cytochrome c oxidase I, translational activator of mitochondrially encoded cytochrome c oxidase I |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Taco1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- rRNA binding
- mRNA binding
- Transcriptional regulator
- ribosome binding
- protein binding
- YebC/PmpR family DNA-binding transcriptional regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Taco1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex IV assembly
- regulation of mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- mitochondrial ribosome binding
- protein binding
- mRNA binding
- rRNA binding