Eepd1 Gene Summary [Mouse]
Predicted to enable DNA binding activity and catalytic activity. Involved in positive regulation of cholesterol efflux. Predicted to be active in plasma membrane. Is expressed in cerebral cortex ventricular layer; dorsal root ganglion; facial ganglion; orbito-sphenoid; and trigeminal ganglion. Orthologous to human EEPD1 (endonuclease/exonuclease/phosphatase family domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eepd1 |
| Official Name | endonuclease/exonuclease/phosphatase family domain containing 1 [Source:MGI Symbol;Acc:MGI:1914734] |
| Ensembl ID | ENSMUSG00000036611 |
| Bio databases IDs | |
| Aliases | endonuclease/exonuclease/phosphatase family domain containing 1 |
| Synonyms | 2310005P05Rik, endonuclease/exonuclease/phosphatase family domain containing 1, HSPC107, KIAA1706, RGD1307401 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eepd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Helix-hairpin-helix domain
- competence protein ComEA helix-hairpin-helix repeat region
- Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
- protein binding
- Helix-hairpin-helix motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Eepd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- positive regulation of cholesterol efflux
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- catalytic activity