Mmd Gene Summary [Mouse]
Predicted to enable protein kinase activity. Predicted to be involved in positive regulation of neuron differentiation; positive regulation of protein kinase activity; and regulation of protein localization. Predicted to be located in Golgi apparatus. Is expressed in several structures, including alimentary system; cerebral cortex; cranial ganglion; musculoskeletal system; and retina. Orthologous to human MMD (monocyte to macrophage differentiation associated). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mmd |
| Official Name | monocyte to macrophage differentiation-associated [Source:MGI Symbol;Acc:MGI:1914718] |
| Ensembl ID | ENSMUSG00000003948 |
| Bio databases IDs | |
| Aliases | monocyte to macrophage differentiation-associated |
| Synonyms | 1200017E07Rik, 1810073C06Rik, Maf, MMA, MMD1, monocyte to macrophage differentiation-associated, PAQR11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mmd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Haemolysin-III related
- protein kinase
- signaling receptor activity
- channel protein, hemolysin III family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- T-cell non-Hodgkin disease
- mature T-cell neoplasia
- Ullrich congenital muscular dystrophy
- COVID-19
- adult T-cell leukemia/lymphoma
- arthritis
role in cell
- apoptosis
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- lysosome
- Golgi Apparatus
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mmd gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of protein kinase activity
- regulation of protein localization
- positive regulation of neuron differentiation
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- membrane
- Golgi apparatus
- lysosomal membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling receptor activity
- protein kinase activity