Hnrnpa0 Gene Summary [Mouse]
Enables mRNA 3'-UTR AU-rich region binding activity. Involved in 3'-UTR-mediated mRNA stabilization; inflammatory response; and response to lipopolysaccharide. Is active in synapse. Is expressed in 3rd ventricle; 4th ventricle; brain; brain ventricular layer; and telencephalon ventricular layer. Orthologous to human HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hnrnpa0 |
| Official Name | heterogeneous nuclear ribonucleoprotein A0 [Source:MGI Symbol;Acc:MGI:1924384] |
| Ensembl ID | ENSMUSG00000007836 |
| Bio databases IDs | |
| Aliases | heterogeneous nuclear ribonucleoprotein A0 |
| Synonyms | 1110055B05RIK, 3010025E17Rik, heterogeneous nuclear ribonucleoprotein A0, hnRNP AQ, HNRPA0, HNRPAO, RGD1563684 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hnrnpa0 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- protein kinase binding
- mRNA 3' UTR binding
- RNA recognition motif
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
- interchromatin granule clusters
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hnrnpa0 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- 3'-UTR-mediated mRNA stabilization
- inflammatory response
- response to lipopolysaccharide
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- synapse
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- RNA binding
- mRNA 3'-UTR AU-rich region binding
- mRNA binding