Id3

Enables several functions, including bHLH transcription factor binding activity; leptomycin B binding activity; and transcription regulator inhibitor activity. Involved in several processes, including negative regulation of myoblast differentiation; notochord development; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to leptomycin B; negative regulation of macromolecule biosynthetic process; and negative regulation of osteoblast differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; metanephros; and sensory organ. Used to study Sjogren's syndrome. Orthologous to human ID3 (inhibitor of DNA binding 3). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Id3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Id3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Id3 gene, providing context for its role in the cell.