Rsph14 Gene Summary [Mouse]
Predicted to be involved in epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and mating. Part of radial spoke. Is expressed in lung epithelium and nasal cavity respiratory epithelium. Orthologous to human RSPH14 (radial spoke head 14 homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rsph14 |
| Official Name | radial spoke head homolog 14 (Chlamydomonas) [Source:MGI Symbol;Acc:MGI:1918486] |
| Ensembl ID | ENSMUSG00000009070 |
| Bio databases IDs | |
| Aliases | radial spoke head homolog 14 (Chlamydomonas) |
| Synonyms | 4933431K05RIK, radial spoke head 14 homolog, radial spoke head homolog 14 (Chlamydomonas), RTDR1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rsph14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Armadillo/beta-catenin-like repeat
- HEAT-like repeat
- Armadillo/beta-catenin-like repeats
- protein binding
- HEAT repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- anorexia
- major depression
- kidney stones
- urolithiasis
- lymphomagenesis
- coronary artery disease
- primary central nervous system lymphoma
- primary cancer
- central nervous system cancer
role in cell
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rsph14 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- motile cilium
- radial spoke
Molecular Function
What the gene product does at the molecular level
- protein binding