Rps25 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in central nervous system and retina. Orthologous to human RPS25 (ribosomal protein S25). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps25 |
| Official Name | ribosomal protein S25 [Source:MGI Symbol;Acc:MGI:1922867] |
| Ensembl ID | ENSMUSG00000009927 |
| Bio databases IDs | |
| Aliases | ribosomal protein S25 |
| Synonyms | 2810009D21Rik, eS25, ribosomal protein S25, S25 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- S25 ribosomal protein
- structural constituent of ribosome
- protein binding
- nuclear matrix targeting site
Pathways
Biological processes and signaling networks where the Rps25 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- autosomal dominant polycystic kidney disease
- acute myeloid leukemia
- nonalcoholic steatohepatitis
- leiomyoma
- leiomyomatosis
regulates
- TP53
- RNR
- MDM2
- Ribosomal Subunit 40s
role in cell
- growth
- activation in
- ubiquitination in
- stabilization in
- induction in
- nuclear export in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
- synapse
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps25 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- ribosomal small subunit biogenesis
- rRNA processing
- translation
Cellular Component
Where in the cell the gene product is active
- postsynaptic density
- nucleus
- extracellular vesicular exosome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- cytoplasm
- cytosol
- small ribosomal subunit
- ribosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome