RPS25 Gene Summary [Human]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Details

Type
Nonsense Mediated Decay
Official Symbol
RPS25
Official Name
ribosomal protein S25 [Source:HGNC Symbol;Acc:HGNC:10413]
Ensembl ID
ENSG00000118181
Bio databases IDs NCBI: 6230 Ensembl: ENSG00000118181
Aliases ribosomal protein S25
Synonyms 2810009D21Rik, eS25, ribosomal protein S25, S25
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPS25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • S25 ribosomal protein
  • structural constituent of ribosome
  • protein binding
  • nuclear matrix targeting site

Pathways

Biological processes and signaling networks where the RPS25 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • autosomal dominant polycystic kidney disease
  • acute myeloid leukemia
  • nonalcoholic steatohepatitis
  • leiomyoma
  • leiomyomatosis
regulated by
regulates
role in cell
  • growth
  • activation in
  • ubiquitination in
  • stabilization in
  • induction in
  • nuclear export in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • ribosome
  • Nucleus
  • cytosol
  • nucleoplasm
  • nucleoli
  • synapse
  • postsynaptic density

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RPS25 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cytoplasmic translation
  • ribosomal small subunit biogenesis
  • rRNA processing
  • translation

Cellular Component

Where in the cell the gene product is active
  • postsynaptic density
  • nucleus
  • extracellular vesicular exosome
  • cytosolic ribosome
  • cytosolic small ribosomal subunit
  • cytoplasm
  • cytosol
  • small ribosomal subunit
  • ribosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.