Rpl19 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to act upstream of or within translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in cumulus oophorus; early conceptus; oocyte; and ovary. Orthologous to human RPL19 (ribosomal protein L19). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl19 |
| Official Name | ribosomal protein L19 [Source:MGI Symbol;Acc:MGI:98020] |
| Ensembl ID | ENSMUSG00000017404 |
| Bio databases IDs | |
| Aliases | ribosomal protein L19 |
| Synonyms | eL19, L19, LOC100910455, Ribosomal protein l19, Rpl19a |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- rRNA binding
- protein binding
- Ribosomal_L19e
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl19 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- Alzheimer disease
- breast cancer
- leiomyoma
- leiomyomatosis
- papillary thyroid carcinoma
- papillary thyroid cancer
role in cell
- production in
- phosphorylation in
- cell death
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- cellular membrane
- ribosome
- cytosol
- nucleoli
- synapse
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- cytosolic ribosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
- synapse
- cytosolic large ribosomal subunit
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome