Tjap1 Gene Summary [Mouse]
Acts upstream of or within Golgi organization. Located in endosome; plasma membrane; and trans-Golgi network. Is expressed in tongue muscle and vertebral axis musculature. Orthologous to human TJAP1 (tight junction associated protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tjap1 |
| Official Name | tight junction associated protein 1 [Source:MGI Symbol;Acc:MGI:1921344] |
| Ensembl ID | ENSMUSG00000012296 |
| Bio databases IDs | |
| Aliases | tight junction associated protein 1 |
| Synonyms | 0610041D19Rik, PILT, tight junction associated protein 1, TJP4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tjap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein incorporated later into Tight Junctions
- Growth-arrest specific micro-tubule binding
- protein binding
- Domain of unknown function (DUF4200)
Pathways
Biological processes and signaling networks where the Tjap1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- perinuclear region
- endosomes
- Golgi Apparatus
- cell-cell contacts
- trans Golgi network
- anchoring junction
- tight junctions
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tjap1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Golgi organization
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- tight junction
- endosome
- Golgi apparatus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding