Ceacam16 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Involved in sensory perception of sound. Located in stereocilium tip. Is expressed in brainstem; metanephros; submandibular gland; and testis. Used to study autosomal dominant nonsyndromic deafness 4A. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 4B and autosomal recessive nonsyndromic deafness 113. Orthologous to human CEACAM16 (CEA cell adhesion molecule 16, tectorial membrane component). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ceacam16 |
| Official Name | carcinoembryonic antigen-related cell adhesion molecule 16 [Source:MGI Symbol;Acc:MGI:2685615] |
| Ensembl ID | ENSMUSG00000014686 |
| Bio databases IDs | |
| Aliases | carcinoembryonic antigen-related cell adhesion molecule 16 |
| Synonyms | B-cell leukaemia/lymphoma 3, CEA cell adhesion molecule 16, CEA cell adhesion molecule 16, tectorial membrane component, CEAL2, DFNA4B, DFNB113, Gm769 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ceacam16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- immunoglobulin variable region-like domain
- protein binding
- identical protein binding
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- familial nonsyndromic hearing impairment
- autosomal dominant deafness type 4B
- ear malformation
- Alzheimer disease
- autosomal recessive deafness type 113
- autosomal recessive deafness
- nonsyndromic hearing impairment
- high-frequency hearing loss
- low-frequency hearing loss
- hearing loss
regulates
role in cell
- cell-cell contact
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- apical compartment
- vesicles
- stereocilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ceacam16 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of sound
Cellular Component
Where in the cell the gene product is active
- extracellular space
- stereocilium bundle tip
Molecular Function
What the gene product does at the molecular level
- identical protein binding