Ppdpf Gene Summary [Mouse]

Acts upstream of or within TORC1 signaling and liver development. Is expressed in several structures, including esophagus; forelimb bud; and male reproductive gland or organ. Used to study metabolic dysfunction-associated steatotic liver disease. Orthologous to human PPDPF (pancreatic progenitor cell differentiation and proliferation factor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ppdpf
Official Name
pancreatic progenitor cell differentiation and proliferation factor [Source:MGI Symbol;Acc:MGI:1913746]
Ensembl ID
ENSMUSG00000016344
Bio databases IDs NCBI: 66496 Ensembl: ENSMUSG00000016344
Aliases pancreatic progenitor cell differentiation and proliferation factor
Synonyms 0610012G23Rik, 2610317A05Rik, 2700038C09Rik, 3110053G12Rik, C20orf149, dJ697K14.9, exdpf, pancreatic progenitor cell differentiation and proliferation factor, RGD1310660
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppdpf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Differentiation and proliferation regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • colorectal cancer
  • organismal death
  • epithelial cancer
  • epithelial neoplasia
  • cancer
  • abdominal cancer
  • schizophrenia
  • pancreatic epithelial cancer
  • pancreatic cancer
regulated by
role in cell
  • expression in
  • phosphorylation in
  • growth
  • accumulation in
  • cellular infiltration by
  • activation
  • number
  • binding in
  • molecular cleavage in
  • ubiquitination in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppdpf gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell differentiation

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.