Ppdpf Gene Summary [Rat]
Predicted to be involved in cell differentiation. Predicted to act upstream of or within TORC1 signaling and liver development. Predicted to be located in mitochondrion. Orthologous to human PPDPF (pancreatic progenitor cell differentiation and proliferation factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppdpf |
| Official Name | pancreatic progenitor cell differentiation and proliferation factor [Source:RGD Symbol;Acc:1310660] |
| Ensembl ID | ENSRNOG00000012722 |
| Bio databases IDs | |
| Aliases | pancreatic progenitor cell differentiation and proliferation factor |
| Synonyms | 0610012G23Rik, 2610317A05Rik, 2700038C09Rik, 3110053G12Rik, C20orf149, dJ697K14.9, exdpf, pancreatic progenitor cell differentiation and proliferation factor, RGD1310660 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppdpf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Differentiation and proliferation regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- colorectal cancer
- organismal death
- epithelial cancer
- epithelial neoplasia
- cancer
- abdominal cancer
- schizophrenia
- pancreatic epithelial cancer
- pancreatic cancer
role in cell
- expression in
- phosphorylation in
- growth
- accumulation in
- cellular infiltration by
- activation
- number
- binding in
- molecular cleavage in
- ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ppdpf gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell differentiation