Mall Gene Summary [Mouse]

Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in several cellular components, including Golgi membrane; clathrin-coated vesicle; and membrane raft. Predicted to be active in membrane. Is expressed in naris. Orthologous to human MALL (mal, T cell differentiation protein like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mall
Official Name
mal, T cell differentiation protein-like [Source:MGI Symbol;Acc:MGI:2385152]
Ensembl ID
ENSMUSG00000027377
Bio databases IDs NCBI: 228576 Ensembl: ENSMUSG00000027377
Aliases mal, T cell differentiation protein-like
Synonyms BENE, mal, T-cell differentiation protein-like, RGD1310869
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mall often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Membrane-associating domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriasis
  • epidermal hyperplasia
regulated by
  • GLI1
  • TNF
  • tretinoin
  • ESR1
  • VEGF
  • dsHIC1-2998
  • cholesterol
  • Bt 549 cells
  • methylnitrosourea
  • 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cell periphery
  • perinuclear region
  • intracellular membranes
  • cellular membrane
  • Plasma Membrane
  • Golgi membrane
  • cytoplasmic vesicles
  • membrane rafts
  • clathrin-coated vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mall gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • myelination
  • cholesterol homeostasis

Cellular Component

Where in the cell the gene product is active
  • membrane raft
  • membrane
  • cytoplasmic vesicle
  • Golgi membrane
  • clathrin-coated vesicle
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural constituent of myelin sheath

Gene-Specific Assays for Results You Can Trust

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