Atp5g3 Gene Summary [Mouse]
The protein encoded by this gene is a subunit of mitochondrial membrane ATP synthase, the enzyme that catalyzes ATP synthesis during oxidative phosphorylation. This gene encodes subunit 9, which is present in multiple copies in the transmembrane part of the ATP synthase complex. Phenotype and gene expression profiles suggest correlations between this gene and alcoholism- and obesity-related phenotypes. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Sep 2014]
Details
| Type | Protein Coding |
| Official Symbol | Atp5g3 |
| Official Name | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) [Source:MGI Symbol;Acc:MGI:2442035] |
| Ensembl ID | ENSMUSG00000018770 |
| Bio databases IDs | |
| Aliases | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) |
| Synonyms | 6030447M23, ATP5G3, ATP synthase membrane subunit c locus 3, ATP Synthase Subunit c, DYTSPG, P3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp5g3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATP synthase subunit C
- PRK13469
- adenosine-tetraphosphatase
- channel/pore class transporter
- ATP synthase, membrane-bound Fo/Vo/Ao complexes, subunit c
- protein binding
- transporter
Pathways
Biological processes and signaling networks where the Atp5g3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial membrane
- mitochondrial inner membrane
- mitoplasts
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp5g3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
- mitochondrial outer membrane
- mitochondrial inner membrane
- mitochondrial proton-transporting ATP synthase complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- hydrogen ion transmembrane transporter activity
- lipid binding