Clvs2 Gene Summary [Mouse]
Predicted to enable phosphatidylinositol-3,5-bisphosphate binding activity. Predicted to be involved in lysosome organization. Predicted to be located in early endosome membrane. Predicted to be active in clathrin-coated vesicle; endosome; and trans-Golgi network. Is expressed in embryo. Orthologous to human CLVS2 (clavesin 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Clvs2 |
| Official Name | clavesin 2 [Source:MGI Symbol;Acc:MGI:2443223] |
| Ensembl ID | ENSMUSG00000019785 |
| Bio databases IDs | |
| Aliases | clavesin 2 |
| Synonyms | A330019N05Rik, bA160A10.4, C6orf212, C6orf213, Clavesin-2, LOC102724729, RGD1306801, RLBP1L2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Clvs2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain in homologues of a S
- CRAL/TRIO, N-terminal domain
- binding protein
- Divergent CRAL/TRIO domain
- CRAL/TRIO domain
- protein binding
- phosphatidylinositol binding
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomes
- trans Golgi network
- clathrin-coated vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Clvs2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lysosome organization
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- trans-Golgi network
- endosome
- clathrin-coated vesicle
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- phosphatidylinositol-3,5-bisphosphate binding