Mtfr2 Gene Summary [Mouse]
Involved in aerobic respiration and mitochondrial fission. Located in mitochondrion. Is expressed in several structures, including heart; liver; lung; spleen; and testis. Orthologous to human MTFR2 (mitochondrial fission regulator 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtfr2 |
| Official Name | mitochondrial fission regulator 2 [Source:MGI Symbol;Acc:MGI:1919054] |
| Ensembl ID | ENSMUSG00000019992 |
| Bio databases IDs | |
| Aliases | mitochondrial fission regulator 2 |
| Synonyms | 2610016C23Rik, 4933412C16Rik, DUFD1, FAM54A, mitochondrial fission regulator 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mtfr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Mitochondrial fission regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mtfr2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- aerobic respiration
- mitochondrion organization
- mitochondrial fission
Cellular Component
Where in the cell the gene product is active
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding