MTFR2 Gene Summary [Human]

Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MTFR2
Official Name
mitochondrial fission regulator 2 [Source:HGNC Symbol;Acc:HGNC:21115]
Ensembl ID
ENSG00000146410
Bio databases IDs NCBI: 113115 Ensembl: ENSG00000146410
Aliases mitochondrial fission regulator 2
Synonyms 2610016C23Rik, 4933412C16Rik, DUFD1, FAM54A, mitochondrial fission regulator 2
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MTFR2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Mitochondrial fission regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • breast cancer
  • serous ovarian cancer
  • diabetic nephropathy
  • serous ovarian adenocarcinoma
regulated by
role in cell
  • organization
  • respiration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MTFR2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • aerobic respiration
  • mitochondrion organization
  • mitochondrial fission

Cellular Component

Where in the cell the gene product is active
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.