Pwwp3a Gene Summary [Mouse]

Predicted to enable nucleosome binding activity. Predicted to be involved in DNA repair and chromatin organization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including foregut; ganglia; midbrain lateral wall; nose; and tooth. Orthologous to human PWWP3A (PWWP domain containing 3A, DNA repair factor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pwwp3a
Official Name
PWWP domain containing 3A, DNA repair factor [Source:MGI Symbol;Acc:MGI:1915364]
Ensembl ID
ENSMUSG00000020156
Bio databases IDs NCBI: 68114 Ensembl: ENSMUSG00000020156
Aliases PWWP domain containing 3A, DNA repair factor
Synonyms 2610019J09, 9430059D04Rik, EXPAND1, HSPC211, MUM, MUM-1, PWWP domain containing 3A, DNA repair factor, UBE-1C2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pwwp3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • PWWP domain
  • PWWP (Pro-Trp-Trp-Pro) domain
  • chromatin binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
  • nonalcoholic fatty liver disease
  • chronic pain
regulated by
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pwwp3a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • DNA repair
  • chromatin organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • nucleosome binding

Gene-Specific Assays for Results You Can Trust

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