Baiap2l1 Gene Summary [Mouse]
Predicted to enable proline-rich region binding activity. Predicted to be involved in actin crosslink formation; actin filament bundle assembly; and positive regulation of actin filament polymerization. Predicted to be located in plasma membrane. Predicted to be active in cytosol and nucleoplasm. Predicted to colocalize with actin cytoskeleton. Is expressed in several structures, including brain; gut; lung; and nose. Orthologous to human BAIAP2L1 (BAR/IMD domain containing adaptor protein 2 like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Baiap2l1 |
| Official Name | BAI1-associated protein 2-like 1 [Source:MGI Symbol;Acc:MGI:1914148] |
| Ensembl ID | ENSMUSG00000038859 |
| Bio databases IDs | |
| Aliases | BAI1-associated protein 2-like 1 |
| Synonyms | 1300006M19Rik, BAI1-associated protein 2-like 1, BAR/IMD domain containing adaptor protein 2 like 1, IRTKS, LOC100128461, RGD1308452 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Baiap2l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- IRSp53/MIM homology domain
- protein binding
- Bin/Amphiphysin/Rvs domain
- inverse-Bin-Amphiphysins-Rvs domain
- Src Homology 3 domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- neoplasia
- breast cancer
- breast carcinoma
- insulin resistance
- organismal death
- androgenic alopecia
- gout
role in cell
- phosphorylation in
- expression in
- proliferation
- binding in
- invasion by
- organization
- sphere formation
- chemotaxis
- stabilization in
- polymerization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- actin cytoskeleton
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Baiap2l1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- actin crosslink formation
- plasma membrane organization
- regulation of actin cytoskeleton organization
- positive regulation of actin filament polymerization
- actin filament bundle assembly
Cellular Component
Where in the cell the gene product is active
- adherens junction
- extracellular vesicular exosome
- actin cytoskeleton
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- proline-rich region binding
- protein binding
- actin binding