Il9r Gene Summary [Mouse]
Enables interleukin-9 receptor activity. Acts upstream of or within B cell activation; immunoglobulin mediated immune response; and regulation of peptidyl-tyrosine phosphorylation. Located in cell surface and plasma membrane. Is expressed in bone marrow. Orthologous to human IL9R (interleukin 9 receptor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Il9r |
| Official Name | interleukin 9 receptor [Source:MGI Symbol;Acc:MGI:96564] |
| Ensembl ID | ENSMUSG00000020279 |
| Bio databases IDs | |
| Aliases | interleukin 9 receptor |
| Synonyms | CD129, IL9-R alpha, IL9-R α, interleukin 9 receptor |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Il9r often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- STAT binding domain
- Box I domain
- FN3
- interleukin-9 receptor
- STAT3 binding domain
- interleukin-9 binding
- membrane-proximal domain
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Il9r gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- tumorigenesis
- colorectal cancer
- asthma
- experimental autoimmune encephalomyelitis
role in cell
- expression in
- growth
- production in
- activation in
- phosphorylation in
- signaling in
- apoptosis
- proliferation
- differentiation
- quantity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Il9r gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- interleukin-9-mediated signaling pathway
- signal transduction
- cytokine-mediated signaling pathway
- immunoglobulin mediated immune response
- regulation of cell proliferation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- external side of plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- interleukin-9 receptor activity
- interleukin-9 binding