Ncbp3 Gene Summary [Mouse]
Enables RNA cap binding activity. Predicted to be involved in defense response to virus; mRNA export from nucleus; and snRNA export from nucleus. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of nuclear cap binding activity complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system. Orthologous to human NCBP3 (nuclear cap binding subunit 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ncbp3 |
| Official Name | nuclear cap binding subunit 3 [Source:MGI Symbol;Acc:MGI:1914124] |
| Ensembl ID | ENSMUSG00000020783 |
| Bio databases IDs | |
| Aliases | nuclear cap binding subunit 3 |
| Synonyms | 1200014J11Rik, C130061O14RIK, C17orf85, ELG, HSA277841, nuclear cap binding subunit 3, RGD1308139 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ncbp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA 7-methylguanosine cap binding
- RNA cap binding
- Nuclear cap-binding protein subunit 3
- mRNA binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ncbp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA export from nucleus
- mRNA transcription from RNA polymerase II promoter
- posttranscriptional gene silencing by RNA
- mRNA capping
- snRNA export from nucleus
- defense response to virus
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear cap binding complex
- RNA cap binding complex
- cytoplasm
- nuclear speck
Molecular Function
What the gene product does at the molecular level
- RNA 7-methylguanosine cap binding
- protein binding
- RNA binding
- RNA cap binding
- mRNA binding