Exoc7 Gene Summary [Mouse]
Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within protein transmembrane transport. Located in growth cone membrane. Is expressed in 1-cell stage embryo; primary oocyte; secondary oocyte; and thymus primordium. Orthologous to human EXOC7 (exocyst complex component 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Exoc7 |
| Official Name | exocyst complex component 7 [Source:MGI Symbol;Acc:MGI:1859270] |
| Ensembl ID | ENSMUSG00000020792 |
| Bio databases IDs | |
| Aliases | exocyst complex component 7 |
| Synonyms | 2-5-3p, BLOM4, EX070, EXO70, Exo70p, EXOC1, exocyst complex component 7, LOC100911734, NEDSEBA, sec70, YJL085W |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Exoc7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- coiled-coil domain
- protein binding
- transporter
- Exo70 exocyst complex subunit
Pathways
Biological processes and signaling networks where the Exoc7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- experimentally-induced diabetes
- neurodevelopmental disorder with seizures and brain atrophy
- complex neurodevelopmental disorder
role in cell
- expression in
- disruption
- accumulation
- formation
- outgrowth
- formation by
- exocytosis by
- secretion
- formation in
- outgrowth in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule fractions
- presynaptic regions
- cell surface
- perinuclear region
- postsynaptic region
- Plasma Membrane
- centrosome
- microtubules
- midbody
- cell-cell contacts
- microtubule organizing centers
- cytosol
- plasma membrane projections
- lateral plasma membrane
- growth cone
- neurites
- perinuclear vesicles
- cell membrane leading edge
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Exoc7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transmembrane transport
- membrane fission
- cytokinesis after mitosis
- vesicle docking involved in exocytosis
- regulation of macroautophagy
- regulation of entry of bacterium into host cell
- exocytosis
Cellular Component
Where in the cell the gene product is active
- microtubule organizing center
- centriolar satellite
- membrane
- cytosol
- growth cone membrane
- midbody
- plasma membrane
- exocyst
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4,5-bisphosphate binding
- protein binding
- protein binding, bridging