Ssc5d Gene Summary [Mouse]
Enables fibronectin binding activity; laminin binding activity; and scavenger receptor activity. Involved in negative regulation of interleukin-8 production and response to bacterium. Acts upstream of or within defense response and regulation of interleukin-8 production. Located in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; forelimb; genitourinary system; and immune system. Orthologous to human SSC5D (scavenger receptor cysteine rich family member with 5 domains). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ssc5d |
| Official Name | scavenger receptor cysteine rich family, 5 domains [Source:MGI Symbol;Acc:MGI:3606211] |
| Ensembl ID | ENSMUSG00000035279 |
| Bio databases IDs | |
| Aliases | scavenger receptor cysteine rich family, 5 domains |
| Synonyms | A430110N23Rik, RGD1565772, S5D-SRCRB, scavenger receptor cysteine rich family, 5 domains, scavenger receptor cysteine rich family member with 5 domains |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ssc5d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Scavenger receptor cysteine-rich domain
- Family of unknown function (DUF5585)
- laminin binding
- scavenger receptor
- extracellular matrix binding
- Metaviral_G glycoprotein
- protein binding
- fibronectin binding
- transmembrane receptor
- Scavenger receptor Cys-rich
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Extracellular Space
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ssc5d gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
- defense response to Gram-negative bacterium
- innate immune response
- negative regulation of interleukin-8 production
- detection of bacterial lipoprotein
- defense response
- defense response to Gram-positive bacterium
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasm
- membrane
- extracellular matrix
Molecular Function
What the gene product does at the molecular level
- extracellular matrix binding
- protein binding
- fibronectin binding
- scavenger receptor activity
- laminin binding