Tm4sf5 Gene Summary [Mouse]
Predicted to enable arginine binding activity. Predicted to be involved in regulation of G1/S transition of mitotic cell cycle. Predicted to be located in lysosomal membrane and plasma membrane. Predicted to be active in membrane. Is expressed in gut; peritoneum; and urinary system. Orthologous to human TM4SF5 (transmembrane 4 L six family member 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tm4sf5 |
| Official Name | transmembrane 4 superfamily member 5 [Source:MGI Symbol;Acc:MGI:1922854] |
| Ensembl ID | ENSMUSG00000018919 |
| Bio databases IDs | |
| Aliases | transmembrane 4 superfamily member 5 |
| Synonyms | 2010003F10RIK, transmembrane 4 L six family member 5, transmembrane 4 superfamily member 5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tm4sf5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- L6 membrane protein
- protein binding
- amino acid binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- tumorigenesis
- metastasis
- cancer
- coronary artery disease
role in cell
- expression in
- migration
- glycolysis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tm4sf5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of G1/S transition of mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- membrane
- lysosomal membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- arginine binding
- protein binding