Lrrc46 Gene Summary [Mouse]
Involved in sperm flagellum assembly. Acts upstream of or within maintenance of cell number; single fertilization; and sperm flagellum assembly. Located in sperm flagellum. Is active in sperm midpiece. Is expressed in 4th ventricle lateral recess; lateral ventricle choroid plexus; and olfactory epithelium. Orthologous to human LRRC46 (leucine rich repeat containing 46). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lrrc46 |
| Official Name | leucine rich repeat containing 46 [Source:MGI Symbol;Acc:MGI:1916547] |
| Ensembl ID | ENSMUSG00000020878 |
| Bio databases IDs | |
| Aliases | leucine rich repeat containing 46 |
| Synonyms | 1700006D24Rik, leucine rich repeat containing 46, MGC16309 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc46 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- leucine-rich repeat
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat
- Leucine Rich repeats (2 copies)
- Leucine-rich repeat, SDS22-like subfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- sperm midpiece
- sperm tail