Tc2n Gene Summary [Mouse]

Located in nucleus. Orthologous to human TC2N (tandem C2 domains, nuclear). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tc2n
Official Name
tandem C2 domains, nuclear [Source:MGI Symbol;Acc:MGI:1921663]
Ensembl ID
ENSMUSG00000021187
Bio databases IDs NCBI: 74413 Ensembl: ENSMUSG00000021187
Aliases tandem C2 domains, nuclear
Synonyms 4933406D09Rik, C14orf47, C2CD1, Membrane targeting c2 domain containing 1, MTAC2D1, TAC2N, tandem C2 domains, nuclear
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tc2n often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein kinase C conserved region 2 (CalB)
  • transporter
  • C2 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • venous thromboembolism
  • acute myeloid leukemia
  • deep vein thrombosis
  • familial adenomatous polyposis
  • coronary artery disease
  • inflammatory bowel disease
  • thromboembolism
  • ischemic stroke
  • gastroesophageal reflux
  • systemic autoimmune syndrome
regulated by
  • methylprednisolone
  • ESR1
  • SNCA
  • estradiol-17beta-benzoate
  • F2
  • bucladesine
  • norepinephrine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • exosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tc2n gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.