Rgs7bp Gene Summary [Mouse]
Involved in regulation of postsynaptic membrane potential. Acts upstream of or within G protein-coupled receptor signaling pathway. Located in cytoplasm; nucleus; and plasma membrane. Is active in glutamatergic synapse; postsynaptic density membrane; and presynaptic membrane. Is expressed in trigeminal ganglion. Orthologous to human RGS7BP (regulator of G protein signaling 7 binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rgs7bp |
| Official Name | regulator of G-protein signalling 7 binding protein [Source:MGI Symbol;Acc:MGI:106334] |
| Ensembl ID | ENSMUSG00000021719 |
| Bio databases IDs | |
| Aliases | regulator of G-protein signalling 7 binding protein |
| Synonyms | A930030I01Rik, AI842293, D13Bwg1146e, R7BP, regulator of G-protein signaling 7 binding protein, regulator of G-protein signalling 7 binding protein, RGD1309360 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rgs7bp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- presynaptic regions
- postsynaptic region
- Nucleus
- Plasma Membrane
- presynaptic membrane
- synaptic membrane
- dendritic spine head
- perikaryon
- axons
- dendritic shafts
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rgs7bp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of postsynaptic membrane potential
- negative regulation of signal transduction
- G-protein coupled receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- presynaptic membrane
- nucleus
- cytoplasm
- dendritic shaft
- perikaryon
- neuron projection
- axon
- dendritic spine head