Mrpl13 Gene Summary [Mouse]
Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of translation. Predicted to act upstream of or within translation. Located in mitochondrial ribosome. Is expressed in several structures, including early conceptus; gonad; palatal shelf; submandibular gland primordium; and telencephalon ventricular layer. Orthologous to human MRPL13 (mitochondrial ribosomal protein L13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Mrpl13 |
| Official Name | mitochondrial ribosomal protein L13 [Source:MGI Symbol;Acc:MGI:2137218] |
| Ensembl ID | ENSMUSG00000022370 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L13 |
| Synonyms | 1110002D09Rik, L13, L13A, L13mt, mitochondrial ribosomal protein L13, RPL13, RPML13, uL13m |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal protein L13
- Ribosomal_L13
- structural constituent of ribosome
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung squamous cell carcinoma
- epithelial cancer
- breast cancer
- organismal death
- colon adenocarcinoma
- colon epithelial cancer
- cervical cancer
- hepatocellular carcinoma
- liver cancer
- prostate cancer
role in cell
- migration
- apoptosis
- cell death
- invasion by
- proliferation
- cell cycle progression
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
- negative regulation of translation
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial ribosome
- ribosome
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- mRNA binding