Mrps18b Gene Summary [Mouse]
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; genitourinary system; heart; and liver. Orthologous to human MRPS18B (mitochondrial ribosomal protein S18B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrps18b |
| Official Name | mitochondrial ribosomal protein S18B [Source:MGI Symbol;Acc:MGI:1914223] |
| Ensembl ID | ENSMUSG00000024436 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein S18B |
| Synonyms | 2400002C15Rik, C6orf14, HSPC183, HumanS18a, mitochondrial ribosomal protein S18B, MRP-S18-2, mS40, PTD017, S18amt, S18mt-b |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrps18b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein S18
- protein binding
Pathways
Biological processes and signaling networks where the Mrps18b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cancer
- neuroblastoma
- neuroblastoma formation
- insulin resistance
- psoriatic arthritis
role in cell
- expression in
- growth
- differentiation
- ubiquitination in
- immortalization
- cell focus formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell junction
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrps18b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cell junction
- mitochondrial small ribosomal subunit
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- structural constituent of ribosome