Mrpl10 Gene Summary [Mouse]
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to act upstream of or within ribosome biogenesis. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL10 (mitochondrial ribosomal protein L10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrpl10 |
| Official Name | mitochondrial ribosomal protein L10 [Source:MGI Symbol;Acc:MGI:1333801] |
| Ensembl ID | ENSMUSG00000001445 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L10 |
| Synonyms | 0610040E02Rik, L10MT, LOC688165, mitochondrial ribosomal protein L10, MRP-L8, RPML8, uL10m |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal_L10_P0
- structural constituent of ribosome
- Ribosomal protein L10
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- squamous cell lung cancer
- lung squamous cell carcinoma
- lung adenocarcinoma
- lung adenocarcinoma formation
- infection by HIV-1
role in cell
- degradation in
- molecular cleavage in
- biogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Mitochondria
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome