Nptxr Gene Summary [Mouse]

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
Nptxr
Official Name
neuronal pentraxin receptor [Source:MGI Symbol;Acc:MGI:1920590]
Ensembl ID
ENSMUSG00000022421
Bio databases IDs NCBI: 73340 Ensembl: ENSMUSG00000022421
Aliases neuronal pentraxin receptor
Synonyms 1200009K17Rik, 1700036C17Rik, 5730406O18Rik, D15Bwg0580e, Neuronal pentraxin receptor, Npcd, NPR, NPTXR isoform 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nptxr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Concanavalin A-like lectin/glucanases superfamily
  • binding protein
  • LamG
  • protein phosphatase binding
  • pentraxin receptor
  • transmembrane receptor

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • morphogenesis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • glutaminergic synapse
  • cell surface
  • Extracellular Space
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nptxr gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.