Nptxr Gene Summary [Rat]
The protein encoded by this gene is an integral membrane protein, and functions as a neuronal receptor. It is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This site is also conserved in human and mouse. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | Nptxr |
| Official Name | neuronal pentraxin receptor [Source:RGD Symbol;Acc:628898] |
| Ensembl ID | ENSRNOG00000016156 |
| Bio databases IDs | |
| Aliases | neuronal pentraxin receptor |
| Synonyms | 1200009K17Rik, 1700036C17Rik, 5730406O18Rik, D15Bwg0580e, Neuronal pentraxin receptor, Npcd, NPR, NPTXR isoform 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nptxr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Concanavalin A-like lectin/glucanases superfamily
- binding protein
- LamG
- protein phosphatase binding
- pentraxin receptor
- transmembrane receptor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cell surface
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nptxr gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- metal ion binding