Bsg Gene Summary [Mouse]
Predicted to enable cell-cell adhesion mediator activity; signaling receptor activity; and virus receptor activity. Involved in neural retina development; photoreceptor cell maintenance; and spermatogenesis. Located in several cellular components, including acrosomal membrane; photoreceptor inner segment; and photoreceptor outer segment. Is expressed in several structures, including alimentary system; brain; early conceptus; eye; and reproductive system. Orthologous to human BSG (basigin (Ok blood group)). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bsg |
| Official Name | basigin [Source:MGI Symbol;Acc:MGI:88208] |
| Ensembl ID | ENSMUSG00000023175 |
| Bio databases IDs | |
| Aliases | basigin |
| Synonyms | 5A11, 5F7, BASIGIN, basigin (Ok blood group), basignin, BASIN, CD147, CE9, EMMPRIN, EMPRIN, HAb18G, HAb18G/CD147, HT-7, OK, Ox47R, TCSF |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bsg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- signaling receptor activity
- viral receptor
- immunoglobulin domain
- ectodomain
- Immunoglobulin I-set domain
- protein binding
- cytoplasmic domain
- transmembrane domain
- Immunoglobulin like
- tail domain
- Immunoglobulin V-set domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- epithelial neoplasia
- cancer
- neoplasia
- albuminuria
- non-small cell lung cancer
- Alzheimer disease
- liver cancer
- liver neoplasia
- digestive system cancer
role in cell
- expression in
- quantity
- apoptosis
- formation
- entrance
- proliferation
- activation in
- cell death
- binding in
- aggregation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- membrane fraction
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- tubular endosomal network
- intracellular membrane-bounded organelle
- Cytoplasm
- cell surface
- apical compartment
- basal compartment
- cellular membrane
- Nucleus
- endosomes
- vesicles
- granules
- cytosol
- endoplasmic reticulum membrane
- lateral plasma membrane
- Golgi membrane
- endosome surfaces
- alpha granules
- acrosome
- growth cone
- neurites
- photoreceptor outer segments
- photoreceptor inner segments
- sarcolemma
- recycling endosomes
- membrane blebs
- GLUT4 vesicles
- membrane rafts
- detergent-soluble fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bsg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- viral entry into host cell
- angiogenesis
- response to mercury ion
- neutrophil chemotaxis
- response to cAMP
- decidualization
- odontogenesis of dentin-containing tooth
- cell surface receptor signaling pathway
- response to peptide hormone stimulus
- embryo implantation
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- acrosomal membrane
- Golgi membrane
- plasma membrane
- photoreceptor outer segment
- endoplasmic reticulum membrane
- endosome
- extracellular vesicular exosome
- focal adhesion
- melanosome
- intracellular membrane-bounded organelle
- sarcolemma
- membrane
- mitochondrion
- photoreceptor inner segment
- basolateral plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- mannose binding
- cadherin binding
- viral receptor activity