Cldnd1 Gene Summary [Mouse]
Located in apical plasma membrane. Is expressed in several structures, including brain; gut; heart; liver; and metanephros. Orthologous to human CLDND1 (claudin domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cldnd1 |
| Official Name | claudin domain containing 1 [Source:MGI Symbol;Acc:MGI:2447860] |
| Ensembl ID | ENSMUSG00000022744 |
| Bio databases IDs | |
| Aliases | claudin domain containing 1 |
| Synonyms | 1110019C08Rik, C3orf4, claudin-25, claudin domain containing 1, CLDN-25, GENX-3745, Z38 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cldnd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PMP-22/EMP/MP20/Claudin family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- detergent resistant lipid raft fraction
- cellular membrane
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cldnd1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- apical plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding