Elavl3 Gene Summary [Mouse]
Enables mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in cell differentiation and nervous system development. Predicted to be part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; enteric nervous system; eye; intestine; and primitive bladder. Orthologous to human ELAVL3 (ELAV like RNA binding protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Elavl3 |
| Official Name | ELAV like RNA binding protein 3 [Source:MGI Symbol;Acc:MGI:109157] |
| Ensembl ID | ENSMUSG00000003410 |
| Bio databases IDs | |
| Aliases | ELAV like RNA binding protein 3 |
| Synonyms | 2600009P04RIK, DKFZP547J036, ELAV like RNA binding protein 3, HU-antigen C, HUC, HUCL, mHuC, PLE21 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Elavl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ELAV/HuD family splicing factor
- RNA recognition motif (RRM) superfamily
- mRNA 3' UTR binding
- RNA recognition motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- glioblastoma
- glioblastoma cancer
- nonconvulsive seizure
- neuroendocrine prostate cancer
- epileptic seizure
role in cell
- expression in
- differentiation
- stabilization in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- polyribosome fractions
- Cytoplasm
- ribosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Elavl3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- cell differentiation
Molecular Function
What the gene product does at the molecular level
- protein binding
- mRNA 3'-UTR AU-rich region binding