Creld2 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity and protein disulfide isomerase activity. Predicted to be an extracellular matrix structural constituent. Located in Golgi apparatus; endoplasmic reticulum; and extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; long bone; and respiratory system. Orthologous to human CRELD2 (cysteine rich with EGF like domains 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Creld2 |
| Official Name | cysteine-rich with EGF-like domains 2 [Source:MGI Symbol;Acc:MGI:1923987] |
| Ensembl ID | ENSMUSG00000023272 |
| Bio databases IDs | |
| Aliases | cysteine-rich with EGF-like domains 2 |
| Synonyms | 5730592L21rik, cysteine-rich with EGF-like domains 2, RGD1310614 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Creld2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FU
- Furin-like repeats
- protein binding
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Golgi Apparatus
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Creld2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- endoplasmic reticulum
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein disulfide isomerase activity
- protein binding
- calcium ion binding