Jpt2 Gene Summary [Mouse]
Predicted to be involved in endocytosis involved in viral entry into host cell and regulation of calcium-mediated signaling. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system and neural retina. Orthologous to human JPT2 (Jupiter microtubule associated homolog 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Jpt2 |
| Official Name | Jupiter microtubule associated homolog 2 [Source:MGI Symbol;Acc:MGI:1196260] |
| Ensembl ID | ENSMUSG00000024165 |
| Bio databases IDs | |
| Aliases | Jupiter microtubule associated homolog 2 |
| Synonyms | 2810430B18Rik, C16orf34, D17Ertd441e, HN1L, Jupiter microtubule associated homolog 2, L11, RGD1305117 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Jpt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- esophageal squamous cell carcinoma
- insomnia
- organismal death
- metastasis
- esophageal squamous cell cancer
- sleep apnea syndrome
regulated by
role in cell
- proliferation
- migration
- upregulation in
- docetaxel sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Jpt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of calcium-mediated signaling
- viral entry into host cell via endocytosis
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding