Prrc2a Gene Summary [Mouse]
Predicted to be involved in cell differentiation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PRRC2A (proline rich coiled-coil 2A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prrc2a |
| Official Name | proline-rich coiled-coil 2A [Source:MGI Symbol;Acc:MGI:1915467] |
| Ensembl ID | ENSMUSG00000024393 |
| Bio databases IDs | |
| Aliases | proline-rich coiled-coil 2A |
| Synonyms | 3110039B05Rik, BAT2, D17H6S51E, D6S51, D6S51E, G2, mKIAA4178, proline-rich coiled-coil 2A, Wbp12 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prrc2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BAT2 N-terminus
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- inguinal hernia
- Takayasu arteritis
- open-angle glaucoma
- autoimmune disease
- inflammatory bowel disease
- schizophrenia
- coronary artery disease
- membranous glomerulonephritis
- cervical carcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prrc2a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- membrane
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding