Rps8 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Is expressed in brain; cerebral cortex ventricular layer; and cortical plate. Orthologous to human RPS8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps8 |
| Official Name | ribosomal protein S8 [Source:MGI Symbol;Acc:MGI:98166] |
| Ensembl ID | ENSMUSG00000047675 |
| Bio databases IDs | |
| Aliases | ribosomal protein S8 |
| Synonyms | eS8, ribosomal protein S8, S8 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Eukaryotic/archaeal ribosomal protein S8e and similar proteins
- protein binding
- Ribosomal protein S8e
Pathways
Biological processes and signaling networks where the Rps8 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pre-ribosome
- cellular membrane
- ribosome
- Nucleus
- Endoplasmic Reticulum
- Mitochondria
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- cytoplasmic translation
- ribosomal small subunit biogenesis
- translation
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- endoplasmic reticulum
- nucleolus
- nucleoplasm
- nucleus
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome