Atp9b Gene Summary [Mouse]
Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in endocytosis; phospholipid translocation; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in endosome; plasma membrane; and trans-Golgi network. Is expressed in several structures, including adrenal gland; alimentary system; liver; nervous system; and thymus. Orthologous to human ATP9B (ATPase phospholipid transporting 9B (putative)). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp9b |
| Official Name | ATPase, class II, type 9B [Source:MGI Symbol;Acc:MGI:1354757] |
| Ensembl ID | ENSMUSG00000024566 |
| Bio databases IDs | |
| Aliases | ATPase, class II, type 9B |
| Synonyms | ATPase, class II, type 9B, ATPASEP, ATPase phospholipid transporting 9B (putative), Atpc2b, ATPIIB, hMMR1, HUSSY-20, IIb, MMR, NEO1L |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp9b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mg2+-ATPase
- phospholipid-translocating P-type ATPase, flippase
- Phospholipid-translocating ATPase N-terminal
- Cation transport ATPase (P-type)
- ATPase, P-type (transporting), HAD superfamily, subfamily IC
- Haloacid Dehalogenase-like Hydrolases
- transporter
- Phospholipid-translocating P-type ATPase C-terminal
- Cation transporting ATPase, C-terminus
- haloacid dehalogenase-like hydrolase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear Golgi regions
- perinuclear region
- cellular membrane
- trans Golgi network
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp9b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid translocation
- retrograde vesicle-mediated transport, Golgi to ER
- endocytosis
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- perinuclear region of cytoplasm
- endosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- ATPase activity
- ATP binding