Gm16286 Gene Summary [Mouse]
Predicted to enable protein N-terminal-serine acetyltransferase activity and protein-N-terminal-glutamate acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation. Predicted to be located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Predicted to be part of NatA complex. Is expressed in brain; heart; liver; metanephros; and testis. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gm16286 |
| Official Name | predicted gene 16286 [Source:MGI Symbol;Acc:MGI:3833940] |
| Ensembl ID | ENSMUSG00000024571 |
| Bio databases IDs | |
| Aliases | predicted gene 16286 |
| Synonyms | BMKS, D18Wsu98e, DIB1, DIM1, SNRNP15, thioredoxin-like 4A, THIOREDOXIN-LIKE protein 4A, TXNL4, U5-15kD, U5-15kDa, XNL4A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gm16286 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- Mitosis protein DIM1
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the Gm16286 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Burn-McKeown syndrome
- global developmental delay with intellectual disability
- cold thyroid nodule
role in cell
- survival
- cell viability
- replication in
- assembly
- splicing by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gm16286 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- RNA splicing, via transesterification reactions
- spliceosomal complex assembly
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- U4/U6 x U5 tri-snRNP complex
- U5 snRNP
- cytosol
- spliceosomal complex
- U2-type precatalytic spliceosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding