Cep170 Gene Summary [Mouse]

Located in centriole. Orthologous to human CEP170 (centrosomal protein 170). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cep170
Official Name
centrosomal protein 170 [Source:MGI Symbol;Acc:MGI:1918348]
Ensembl ID
ENSMUSG00000057335
Bio databases IDs NCBI: 545389 Ensembl: ENSMUSG00000057335
Aliases centrosomal protein 170
Synonyms 4933426L22RIK, A330004A13Rik, CE170, centrosomal protein 170, FAM68A, KAB, KAB1, Karp1 Binding Protein2, KIAA0470, LOC100909664, Rhk1
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep170 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CEP170 C-terminus
  • Inner membrane component of T3SS, cytoplasmic domain
  • FHA domain
  • Forkhead associated domain
  • protein binding
  • forkhead associated (FHA) domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • bronchopulmonary dysplasia
  • pain
  • lung carcinoma
  • hypertension
  • lung carcinoma process
regulated by
  • BSG
  • Immunoglobulin
  • tetradecanoylphorbol acetate
  • ionomycin
  • androgen
  • PLK1
  • CST5
  • KIF2A
  • CG
  • WPMY-1 cells
role in cell
  • morphology
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • basal bodies
  • centrosome
  • centriole
  • microtubules
  • cytosol
  • spindle fibers
  • astral microtubules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep170 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • centriole
  • spindle
  • cytosol
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.