Aldh1a7 Gene Summary [Mouse]

Predicted to enable 3-deoxyglucosone dehydrogenase activity and benzaldehyde dehydrogenase (NAD+) activity. Involved in fructose catabolic process. Predicted to be located in cytosol. Is expressed in genitourinary system; liver; and pancreas. Orthologous to human ALDH1A1 (aldehyde dehydrogenase 1 family member A1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Aldh1a7
Official Name
aldehyde dehydrogenase family 1, subfamily A7 [Source:MGI Symbol;Acc:MGI:1347050]
Ensembl ID
ENSMUSG00000024747
Bio databases IDs NCBI: 26358 Ensembl: ENSMUSG00000024747
Aliases aldehyde dehydrogenase family 1, subfamily A7
Synonyms Ahd2-like, aldehyde dehydrogenase family 1, subfamily A7, ALDH1A4, Aldh-pb, Raldh2
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Aldh1a7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Aldehyde dehydrogenase family
  • 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
  • betaine-aldehyde dehydrogenase
  • aldehyde dehydrogenase (NAD)
  • enzyme
  • methylmalonic acid semialdehyde dehydrogenase
  • 2-hydroxymuconic semialdehyde dehydrogenase
  • delta-1-pyrroline-5-carboxylate dehydrogenase (PutA C-terminal domain)
  • NAD(P)+-dependent aldehyde dehydrogenase superfamily

Pathways

Biological processes and signaling networks where the Aldh1a7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • alloxan-induced diabetic nephropathy
regulated by
regulates
  • HOXB1
  • tretinoin
  • alitretinoin
  • 9-cis-retinol
  • retinaldehyde
  • xenobiotic
  • D-fructose
  • 9-cis-retinal
  • propionaldehyde
  • HOXA1
role in cell
  • migration
  • outgrowth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • vesicles
  • cytosol

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.